The 34-year-old's stunning overhead kick for Real in the quarter-finals in Turin last April had dumped Juventus out of the tournament once again.
Simeone added: "I don't think it was our worst performance, nor did I see a lack of character".
Diego had made the same gesture when his team beat Juventus in late February, so Cristiano got the last laugh, as well as the honor of knocking Atletico out and moving his team on to the Champions League quarterfinals.
"The Champions League is a hard competition and ties are played over two legs, so comebacks can happen if two teams are balanced".
Midfielder Koke warned they were ready for a "battle" with Juventus, who are dominant in Italy but have struggled to turn domestic success into European glory.
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It is nearly four years since a team featuring Ronaldo was knocked out of the Champions League and he could still win the competition for a fourth consecutive season.
"This had to be a great night and it was one, not just for my goals but for the team", he told Sky Sport Italia.
"That is the sort of mentality you need to win the Champions League".
"We hope the VAR keeps improving and helping make things right, but do you really believe that a person who is 1.87-meters tall can fall that way in a game action like the one with Morata?" said Simeone, who celebrated his team's first goal with an obscene gesture and could face UEFA sanctions.
It was his eighth hat-trick in the Champions League, pulling him level with Barcelona's Lionel Messi, and took the Portugal international's tally in his favourite club competition, where he is the all-time leading scorer, to 124.
The Portuguese has been directly involved in 77 goals in 77 Champions League knockout appearances - 63 goals and 14 assists.
He had scored 10 goals in his seven Champions League games against Juve while at Real, but had struggled this season in Europe after moving to Turin, scoring just once.