At one point during her rant Samantha proclaimed that the Duchess of Sussex "wasn't much different than Trump" - clearly failing to see the irony that it was her, not Meghan, coming up with Trump-esque insults on Twitter.
There is also the issue of leaks - Meghan flew to Toronto last month for a private visit to see her long-time best friend Jessica Mulroney, a Toronto-based stylist who helped plan her wedding, and she chose to stay at her family home to avoid any media intrusion.
One insider tells the outlet that 'She's finding it hard to know who to trust'. "The duchASS can bow to the daddy", Samantha wrote on Twitter.
Just three days ago, the 53-year-old called her sister "the duchASS". No one wants to spoil her marriage and marriage is not at issue.
Russia collusion probe: Ex-Trump campaign aide Papadopoulos jailed
US President Donald Trump reacted by taking an apparent swipe at the cost of the investigation into the former aide. In response, defense lawyer Thomas Breen said his client was "remorseful" that his lies impeded the investigation.
It comes after Thomas Markle revealed his fears Meghan was masking the stresses of royal life with a smile and that the royals were freezing him out of his daughter's life over his staged paparazzi pictures and controversial interview with Good Morning Britain.
"I don't believe she gave him enough of an opportunity". I don't know. It really worries me. "He's got a real soft spot for her and thinks she's the best thing to have happened to Harry".
"There's a high price to pay to be married to that family".
So it should come as no surprise that Meghan is reportedly having a hard time figuring out who she can trust. While her mother Doria Ragland recently made the move to the United Kingdom to be closer to her daughter, she's very publicly estranged from much of the rest of her flesh and blood.
The Australian gossip weekly New Idea also reported that a source from Kensington Palace confirmed the pregnancy.