"With current America and these policies, there will definitely not be the possibility of dialogue and engagement, and the United States has shown that it is totally unreliable", foreign ministry spokesman Bahram Qasemi told a weekly news conference on Monday.
The Trump administration had two main concerns with Obama's JCPOA.
Trump's latest stance towards Tehran runs counter to his recent threatsagainst the nation as well as pulling Washington out of the Iran nuclear deal despite having the support of nearly all US allies.
"We've said this before", said the former Central Intelligence Agency chief.
Ali Motahari, the deputy speaker of Iran's parliament, said that now that the US has withdrawn Iranian engagement could be interpreted as a sign of weakness.
"I believe in meeting", Trump said Monday.
After a meeting with Italian Prime Minister Giuseppe Conte at the White House on Monday, the United States president expressed his willingness to reopen negotiations with Iran in an unusually soft tone.
Iran's interior minister chimed in that Tehran did not trust Washington as a negotiating partner.
Ayatollah Ali Khamenei, right, leading the Eid al-Fitr prayers at the Imam Khomeini grand mosque in the capital Tehran on June 15, 2018.
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The game appeared to be heading for a draw until Tosin Adarabioyo crashed into Dominic Solanke in the area for a certain penalty. He started just one of City's opening six games of the season, playing a meagre total of just 162 minutes.
" 'Trump may take advantage of this over-excitement, ' he said, the state-run IRNA news agency reported". "It could be a test for us".
President Trump emphasized his desire to work out a better deal to ensure Iran never gets hold of a nuclear weapon.
"I don't know what the President hopes to achieve with that meeting", he said in an interview with CNN's Wolf Blitzer on "The Situation Room".
US pastor Andrew Craig Brunson is escorted by Turkish plainclothes police officers from his house in Izmir, Turkey, on July 25.
"I believe they will wind up wanting to meet". He reflected on his "so positive" meeting with dictator Kim Jong-un and "great meeting" with Russian President Vladimir Putin of Russia. Washington ramped up political pressure on Tehran and vowed to re-impose sanctions on the nation.
The remark sent a spark of anticipation in diplomatic circles despite the President's recent testy twitter message to Iran because of the rapidity with which he turned around on North Korea, with whose leadership he exchanged far more sulfurous insults.
Mr Rouhani earlier said that war with Iran would be "the mother of all wars".
With the first USA sanctions due to come into effect next Monday, the economy in Iran has already been hit, giving rise to growing fears of prolonged economic suffering.
Another round, covering other types of commerce, including oil purchases, goes into effect November 4.