Germany manager Joachim Löw revealed his final squad that will be travelling to Russian Federation later this month to compete in the greatest tournament in world football.
Sane scored 10 English Premier League goals and assisted on 15 this past season.
Germany have included 2014 World Cup-winning goalkeeper Manuel Neuer in their final squad for the 2018 tournament on Monday, even though he has only just returned from a long-term absence through injury.
Manuel Neuer - who hadn't played a competitive game since September until the side's friendly loss to Austria on Saturday - was included for the tournament in Russian Federation.
The 22-year-old was a shock omission from Joachim Low's final 23-man party for the tournament in Russian Federation, having starred in City's record-breaking Premier League campaign and been a regular in Germany's recent matches. As Deutsche Welle pointed out, Sane's 3,618 minutes in all competitions for Manchester City were more than three wingers who were chosen by Loew: Bayer Leverkusen's Julian Brandt (2,731), Paris Saint-German's Julian Draxler (2,630) and Borussia Dortmund's Marco Reus (1,163).
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Germany captain Neuer, who won the World Cup four years ago, will also be their first choice keeper for the tournament, ahead of designated number two Marc-Andre ter Stegen and Kevin Trapp.
"It's like being at the airport check-in counter en route to Moscow and you are not allowed to board the plane". But Loew denies that there were any off-field issues contributing to his decision leave Sane off the World Cup roster.
Loew announced his squad at the end of a training camp at the Italian Alps.
Neuer had been out with a repeat of the fracture in his left foot but played the full game against Austria, likely forcing Marc-Andre ter Stegen to the bench.
Germany are set to open their 2018 campaign against Mexico on June 17, before going on to face Sweden and South Korea in their other Group F fixtures.