None of the Israeli fighters suffered any damage despite anti-aircraft firing from Syria, he added.
All night, drones buzzed overhead, heard but not seen in the darkness.
The Syrian Observatory for Human Rights, a monitoring group, said that casualties were expected, although it did not provide a number.
A Syrian SA-22 battery targeted by the Israeli Air Force.
Israel carried out the raids after it said 20 rockets, either Fajr or Grad type, were fired from Syria at its forces in the occupied Golan Heights at around midnight.
Iran "crossed a red line" when it attacked Israel directly from Syria, Netanyahu stated, warning Assad that "whoever hurts us, we will hurt them sevenfold".
"If there is rain on our side, there will be a flood on their side", Liberman said. "I hope that we ended this chapter and that everyone understood".
"The Israeli army carried out an extensive attack against Iranian targets in Syria".
Interfax reported that Syria, which uses Russian-made aerial defenses, intercepted about half of the Israeli missiles. It was the biggest Israeli strike in Syria since the 1973 war. The IDF released a map showing a list of targets it said it hit.
With the latest escalation, Russian Federation is seen by many observers as the key to possibly defusing the situation between Israel and Iran, as it enjoys warm relations with both countries and is the major military power on the ground in Syria.
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Rouhani did not mention Israel's strikes against what the Jewish state said were Iranian targets in Syria, or those against the Israeli-occupied Golan Heights. The Iranian Military Guard is its most elite unit, which also acts as something of its own state within Iran, and it has been spreading itself out across Syria. Israel says its occasional strikes in Syria aim to foil that.
President Donald Trump cited information gathered by Israeli intelligence as part of the rationale behind pulling out of the Iran nuclear deal that the Obama administration had signed with Iran.
"Iranian forces will need months to recover from the strikes", Manelis told Israeli army radio. Israel has not commented on the strike.
Iran's ability to hit back could be limited.
There has been tension between the two Middle Eastern countries for quite some time, and at this point, Israel has appeared to hit a breaking point because of its perception that Iran has too much influence in the region. Iran has vowed to retaliate. This would allow them to attack Israel not only from Lebanese soil - where Israel waged a destructive war with Hezbollah in 2006 - but also from across the border. "Certainly, it is Israel's right to take such steps as necessary to defend itself against this aggression". "This could potentially allow Russian Federation frankly to come out as the victor, if both sides are weakened as the result of a conflict, and this is also a typical Kremlin playbook-play everyone else off against the other so that you come out on top".
"We believe that all issues must be resolved through dialogue", said Lavrov.
Iran has sent thousands of personnel over the years to shore up President Bashar Assad's forces in his fight against an insurgency.
The relationship between Israel and Iran regime is full of tension and has been for years.
Missile fire over Daraa, Syria, on Thursday. He also took aim at the U.S., saying the Russians "know that the agenda of the deep state in the United States is to create a conflict".
Israel insisted it did not want to escalate the situation and encouraged its citizens to continue their daily routine.