In December, Meghan's half-sister, Samantha Markle, fired back at Prince Harry after he called the royals the family that Meghan's 'never had'.
The letter, published by In Touch, begins with a melodramatic: "Dear Prince Harry, it's not too late".
'What kind of person starts out by using her own father until he's bankrupt, then forgets about him in Mexico leaving him broke, over mostly all her debts, ' his letter continued. "She easily forgets if it wasn't for my father, she would be busing tables and baby sitting to pay her old debt off".
"It's very apparent that her tiny bit of Hollywood fame has gone to her head", he wrote.
It's set to be the wedding of the year, packed full of Hollywood's elite and the who's who of the royal family.
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This isn't the first time Thomas has publically spoken out against his sister.
The royals have given an official reason as to why this is - the wedding, unlike elder brother Prince William and the Duchess of Cambridge Catherine's wedding, isn't a formal state event since Harry's the younger brother and all and sixth-in-line.
"Her own father didn't get an invite", he wrote. They were no doubt separated by a generation and presumably by other family circumstances, including the fact that Markle Sr. divorced Meghan's yoga instructor mother, Doria Ragland, when Meghan was 6. "Diana was worshiped by everyone in the world". He even told the Daily Mirror: "She is giving the greatest performance of her life".
Kensington Palace says the couple hope it "will likely be a memorable second for everybody who has gathered collectively in Windsor to benefit from the ambiance of this big day". In April he accused Meghan of falsely trying to portray herself as the new Princess Diana.
'That's what Meg wants, but I don't think that's going t happen. "She's not genuine like Diana", Markle Jr.
Harry and his American fiancee will ride in an Ascot Landau carriage when they take a tour through the town after the wedding ceremony at Windsor Castle, Queen Elizabeths home, to the west of London, on May 19.